Proceedings of a meeting held in April 1992 at Cumberland Lodge in Windsor Great Park, Berkshire, UK, Includes bibliographical references and index, 1. Change as a dominant theme in science / Malcolm Lader -- 2. Alcohol, drug, and tobacco dependence: charting and comparing the likelihood and time-course of relapse and recovery / Colin Taylor -- 3. The changing pharmacology of addiction / David Nutt -- 4. Can psychology make sense of change? / Robin Davidson -- 5. Dependence and the correlates of change: a review of the literature / Reginald G. Smart -- 6. The image of 'progressive disease' / Mary Alison Durand -- 7. Understanding smoking relapse: predisposing factors, precipitating factors, and a combined model / Stephen Sutton -- 8. Environmental influences which promote or impede change in substance behaviour / Harald K.-H. Klingemann -- 9. Economic influences on change in population and personal substance behaviour / Christine Godfrey -- 10. Diffusion of innovation as a model for understanding population change in substance use / Roberta Ferrence, 11. Ideological beliefs influence the feasibilities for policy change / Charles R. Schuster -- 12. Multiple indicators of change: can we identify the dimensions? / John Strang -- 13. Change in the addictions: does treatment make a difference? What smoking research can tell / Martin Jarvis -- 14. Technical habiliments, science, and the clinical frontline: asking some questions / Griffith Edwards